Arakawa, Hiromu. Fullmetal Alchemist       
As young boys, Edward & Alphonse Elric dabbled in alchemy to try to resurrect their dead mother. As a result, Ed lost one arm and one leg, while Al lost his entire body and had his spirit sealed into a suit of armor. Now, they are searching for the fabled Philosopher's Stone to restore what they've lost.

Kamio, Yoko. Boys over Flowers
A girl from a middle class family goes to a private high school dominated by spoiled rich children. Despite constant bullying by many students, she wins the attention of the leader of one of the boys' groups. Eventually the students begin to learn that is more to a person than their wealth.

Kishimoto, Masashi.  Naruto             
"In another world, ninja are the ultimate power--and in the village of Konohagakure live the stealthiest ninja in the world. But twelve years ago Konohagakure was attached by a nine-tailed fox demon which claimed the life of  the village champion. Today, peace has returned, and a troublemaking orphan named Uzumaki Naruto is struggling to graduate from the ninja Academy. But unknown to Naruto and his classmates, within him is a terrifying force ..."

Satrapi, Marjane. Persepolis
An autobiography in comic book form. Marjane grew up in Iran in the midst of many changes for her country and her family. What is to become of a childhood in the midst of the Islamic Revolution?

Thompson, Craig. Blankets
Craig illustrates his own story of growing up with his younger brother and falling in love for the first time.

Tsuda, Masami. Kare Kano: His and her circumstances
Volume one introduces us to Yukino, who is perfect at school while hiding a different version of herself at home. But everything gets turned upside down when she meets her competition, Soiichiro, who sees the true her.

Takaya, Natsuki. Fruits Basket

Tohru Honda was an orphan when one day fate kicked her out of the house and on to land belonging to the mysterious Sohma family. After stumbling upon the teenage squatter, the Sohmas invite Tohru to stay in their house in exchange for cooking and cleaning. Everything goes well until she discovers the Sohma family's secret, when hugged by members of the opposite sex, they turn into their Chinese Zodiac animal!

Spiegelman, Art. Maus: A Survivor's Tale

The author tells his father's true experience of the Holocaust in comic form, featuring animals.